Junior Research Scientist in intestinal physiology in herbivores


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INRAE presentation

The French National Research Institute for Agriculture, Food, and the Environment (INRAE) is a public research establishment under the dual authority of the Ministry of Agriculture and the Ministry of Research.

INRAE is recruiting researchers by open competition and offering permanent position.

It is a major player in research and innovation created on 1st of January 2020. INRAE is a research institute resulting from the merger of INRA and IRSTEA. It is a community of 12,000 people with more than 200 research units and 42 experimental units located throughout France.

The institute is among the world leaders in agricultural and food sciences, in plant and animal sciences, and is 11th in the world in ecology and environment. INRAE’s main goal is to be a key player in the transitions necessary to address major global challenges. In the face of the increase in population, climate change, scarcity of resources and decline in biodiversity, the institute develops solutions for multiperformance agriculture, high quality food and sustainable management of resources and ecosystems.

Work environment, missions and activities

The Herbivores Joint Research Unit (UMR), located near Clermont-Ferrand, conducts research into economically and environmentally efficient herbivore farming, making the most of forage and other resources not used for human consumption. As part of this joint research unit, you will join the "Biomarkers of performance, adaptation and quality" team, which is made up of around twenty permanent staff from INRAE and Bordeaux ScienceAgro. The team's aim is to identify the metabolic and physiological mechanisms controlling the plasticity of tissues that determine ruminant production, efficiency and adaptive responses, and to design tools for phenotyping production traits and product quality.
The aim of your research project will be to study intestinal physiology in cattle, with a particular attention to its secretory function and how this organ is involved in the communication with peripheral tissues and the regulation of food intake. This knowledge will be used to identify practices for maximising efficiency and optimising the use of resources by animals in order to meet the challenges of the agro-ecological transition of livestock farms.

First, you will determine the range of hormones and peptides secreted by the intestine of ruminants.
Secondly, you will seek to understand the relationships between the proteins secreted and the functioning of peripheral organs that are important for growth, milk production or meat quality. The challenge will be to identify biomarkers of phenotypes as a function of rearing practices and to identify levers for modulating phenotypes.
Thirdly, you will develop in vitro approaches to study and understand the mechanisms of action of intestinal protein biomarkers on key tissues in cattle production (liver, muscle, adipose tissue, mammary gland). In the longer term, you will be able to integrate the relationships between the endocrine function of the intestine and the microbiota that this organ harbours, or the link between inflammation and the integrity of the intestinal epithelium.

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Training and skills

PhD or equivalent

PhD level or equivalent.
Skills in animal physiology are required, with a focus on endocrinology if possible. Skills in "omics" analysis will be appreciated. If you do not already have experience in animal experimentation, you will need to be trained to enable you to conduct animal experiments. An interest in working with farmed ruminants is required. You must be able to work in a team.
Fluency in written and spoken English is highly desirable, as is long-term international experience: successful candidates who have not already had such experience will be required to spend time abroad at the end of the internship year.

INRAE's life quality

By joining our teams, you benefit from:

- 30 days of annual leave + 15 days "Reduction of Working Time" (for a full time);
- parenting support: CESU childcare, leisure services;
- skills development systems: training, career advise;
- social support: advice and listening, social assistance and loans;
- holiday and leisure services: holiday vouchers, accommodation at preferential rates;
sports and cultural activities;
- collective catering.

For international scientists: please visit your guide to facilitate your arrival and stay at INRAE

Offer reference

  • Profile number: CR-2024-PHASE-1
  • Corps: CR
  • Category: A
  • Open competition number: 15
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