Temporary position OT-28365
Analytical chemist
31077 Toulouse
INRAE presentation
The French National Research Institute for Agriculture, Food, and Environment (INRAE) is a major player in research and innovation. It is a community of 12,000 people with 272 research, experimental research, and support units located in 18 regional centres throughout France. Internationally, INRAE is among the top research organisations in the agricultural and food sciences, plant and animal sciences, as well as in ecology and environmental science. It is the world’s leading research organisation specialising in agriculture, food and the environment. INRAE’s goal is to be a key player in the transitions necessary to address major global challenges. Faced with a growing world population, climate change, resource scarcity, and declining biodiversity, the Institute has a major role to play in building solutions and supporting the necessary acceleration of agricultural, food and environmental transitions.
Work environment, missions and activities
MetaboHUB (MTH) is the national French metabolomics and fluxomics infrastructure. Launched in 2013, MTH is a leading international infrastructure serving more than 700 scientists worldwide. MetaboHUB gathers 6 regional nodes including more than 150 permanent staffs (79 FTP), 16 NMRs, 71 MS, robotic and computational platforms. MTH aims at pushing forward the field to develop metabolomics, lipidomics and fluxomics from single cell to populations. Your contribution will serve a broad range of researchers in the fields of biotechnologies, Human health and nutrition and plant science. Joining MTH, you will be involved in cutting edge research within a highly skilled and motivated consortium.
With the objective of extending the application of fluxomics to complex biological systems, this project aims to improve workflows to increase the coverage of polar and apolar metabolomes during in vivo isotope tracing studies in complex biological systems (e.g., mouse, fish). The recruited person will have to take in charge the optimisation of sample preparation (biofluids, tissues, etc…), performing isotope profiling analyses using GC & LC-MS/MS, and processing data. Another prospect will be the development of click chemistry, especially for labelled lipidome investigations.
In close collaboration with Lipidomic and FluxoVivo MetaToul Teams, the recruited person will develop and optimize methods and protocols (specific and dual extractions) to extract metabolites from different types of samples and analyze them using various analytical systems (GC & LC coupled with low and high-resolution mass spectrometers). Processing isotope labelled data will require special software optimization.
Training and skills
Academic
Master chemistry
Compulsory skills Skills in French language are not a prerequisite.
English is mandatory
Attraction for analytical chemistry
Mass Spectrometry (LC/MS & GC/MS)
INRAE's life quality
By joining our teams, you benefit from (depending on the type of contract and its duration):
- up to 30 days of annual leave + 15 days "Reduction of Working Time" (for a full time);
- parenting support: CESU childcare, leisure services;
- skills development systems: training, career advise;
- social support: advice and listening, social assistance and loans;
- holiday and leisure services: holiday vouchers, accommodation at preferential rates;
- sports and cultural activities;
- collective catering.
How to apply
I send my CV and my motivation letter
All persons employed by or hosted at INRAE, a public research establishment, are subject to the Civil Service Code, particularly with regard to the obligation of neutrality and respect for the principle of secularism. In carrying out their functions, whether or not they are in contact with the public, they must not express their religious, philosophical or political convictions through their behaviour or by what they wear. > Find out more: fonction publique.gouv.fr website (in French)