The French National Research Institute for Agriculture, Food, and the Environment (INRAE) is a public research establishment. It is a community of 12,000 people with more than 200 research units and 42 experimental units located throughout France. The institute is among the world leaders in agricultural and food sciences, in plant and animal sciences, and is 11th in the world in ecology and environment. INRAE’s main goal is to be a key player in the transitions necessary to address major global challenges. In the face of the increase in population, climate change, scarcity of resources and decline in biodiversity, the institute develops solutions for multiperformance agriculture, high quality food and sustainable management of resources and ecosystems.
Work environment, missions and activities
- You will be welcomed in the GenPhySE research unit, INRAE, Toulouse, France (https://genphyse.toulouse.inra.fr/groups/genepi), as part of the GEroNIMO project funded by the European Horizon 2020, entitled "Genome and epigenome enabled breeding in monogastrics" (https://www.geronimo-h2020.eu/).
GEroNIMO is a large scale project involving 21 partners from 11 European Countries that aims to provide chicken and pig breeders with new knowledge and tools to promote innovative genome- and epigenome enabled selection methods, to move toward more sustainable breeding models. GEroNIMO is part of the EuroFAANG effort (https://eurofaang.eu/).
You will be based in Toulouse at INRAE and will join a multi-disciplinary environment of geneticists, bioinformaticians and biostatisticians. You will take a leading role in the data analysis and will be expected to use your initiative and creativity to identify areas for research development.
- You will lead projects using epigenomic data obtained from large pig and chicken populations to study the genetic and epigenetic contributions to phenotypic variation, to assess DNA methylation footprints of selection and of environmental factors, and to estimate the extent of transgenerational epigenetic inheritance.
You will be in charge of:
- Analyzing high-throughput epigenomics data generated for the GEroNIMO project
- Leading transgenerational analyses (phenotypes, genotypes and DNA methylation data will be available for 3 generations in quail, from 1360 animals)
- Studying the effect of the environment (heat stress, feed stress or age) on the epigenome
- Participating in deciphering the genome-to-phenome relationship (eQTL, meQTL, EWAS)
- Performing (FAIR) data management and submission
- Closely interacting with other members of the GEroNIMO consortium
- Possibility of teleworking - Starting date: between September 2022 and January 2023
- Possibility of teleworking
- Starting date: between September 2022 and January 2023
Training and skills
- Recommended training: PhD in genetics/epigenetics/bioinformatics
- Knowledge required: Proficiency in UNIX command line and high-performance computing with experience with Next Generation Sequencing data analysis. Documented skills in verbal and written communication in English
- Skills sought: High enthusiasm and team player attitude, independent thinking (Being a fan of The Little Prince would be a little plus ;-)…).
No need to speak French to apply to this position, although a scholar level may be useful for the daily life in Toulouse.
INRAE's life quality
By joining our teams, you benefit from (depending on the type of contract and its duration):
- up to 30 days of annual leave + 15 days "Reduction of Working Time" (for a full time);
- parenting support: CESU childcare, leisure services;
- skills development systems: training, career advise;
- social support: advice and listening, social assistance and loans;
- holiday and leisure services: holiday vouchers, accommodation at preferential rates;
- sports and cultural activities;
- collective catering.