The French National Research Institute for Agriculture, Food, and the Environment (INRAE) is a public research establishment under the dual authority of the Ministry of Agriculture and the Ministry of Research.
INRAE is recruiting researchers by open competition and offering permanent position.
It is a major player in research and innovation created on 1st of January 2020. INRAE is a research institute resulting from the merger of INRA and IRSTEA. It is a community of 12,000 people with more than 200 research units and 42 experimental units located throughout France.
The institute is among the world leaders in agricultural and food sciences, in plant and animal sciences, and is 11th in the world in ecology and environment. INRAE’s main goal is to be a key player in the transitions necessary to address major global challenges. In the face of the increase in population, climate change, scarcity of resources and decline in biodiversity, the institute develops solutions for multiperformance agriculture, high quality food and sustainable management of resources and ecosystems.
Work environment, missions and activities
The Fish Physiology and Genomics Institute (LPGP), located on the Beaulieu university campus in Rennes, is developing research on fish reproduction and growth based on physiology and molecular biology (transcriptomic and epigenetic approaches) and functional genomics.
Within this laboratory, you will join the Sexuality, Ovogenesis and Behavior team, made up of 10 permanent staff, which conducts work in the field of the evolution of genes and genomes and reproduction in fish. Your project will consist, through comparative genomics approaches, in producing knowledge on the conservation of regulatory mechanisms underlying the development of certain phenotypes of interest and in particular those that control the differences in fecundity between species.
This will first require the implementation of tools for annotating genes and their regulatory elements, and then developing comparative genomics approaches to simultaneously analyze the evolution of genes and their regulation. For this, you will rely on pre-existing tools for the automatic generation of genomic atlases of conserved regulatory elements in order to then be able to develop comparative mapping approaches integrating both the genes encoding proteins and their regulatory elements. In the medium term, these integrated databases will be used to look for, by multiple and supervised comparisons (possibly via deep learning approaches) of signs of association between the phenotypes of interest and the conserved regulatory regions associated with these phenotypes.
You will eventually be able to broaden your research to other major and contrasting phenotypes of interest in fish.
Training and skills
Candidates must have a PhD or equivalent.
Doctoral level or equivalent. A proven competence in comparative bio-analysis of genomes including a strong expertise and experience in bioinformatics data processing, as well as proven skills in algorithmics and statistical processing are required. Knowledge of reproductive biology and issues related to complete duplications of genomes will be appreciated.
Fluency in English is desirable as well as long-term international experience: successful candidates who have not yet had one will have to spend time abroad at the end of the internship year.
INRAE's life quality
By joining our teams, you benefit from:
- 30 days of annual leave + 15 days "Reduction of Working Time" (for a full time);
- parenting support: CESU childcare, leisure services;
- skills development systems: training, career advise;
- social support: advice and listening, social assistance and loans;
- holiday and leisure services: holiday vouchers, accommodation at preferential rates;
- sports and cultural activities;
- collective catering.